Non fatal pulmonary haemorrhage associated with nitrofurantoin.

Fatal liver necrosis associated with the use of nitrofurantoin.

Fatal pulmonary haemorrhage following adenovirus infection.

Adenoviruses (AdVs) are non-enveloped, doublestranded DNA viruses that vary in size from 70 to 100 nm. AdV infections commonly affect infants and children aged around 5 months to 6 years [1]. They are common pathogens of respiratory and gastrointestinal tracts, urethral canal and eyes characterised by self-limiting infection although fatal infections can occur in the immuno-compromised and occa...

Fatal Nitrofurantoin-Induced Pulmonary Toxicity: A Potentially Preventable Medical Error

The majority of patients affected with nitrofurantoin pulmonary toxicity are elderly women [1]. The proposed mechanism of toxicity is either idiosyncratic oxydant-mediated tissue injury by nitrofurantoin metabolites causing depletion of cellular glutathione (chronic form) or by immunological response induced by nitrofurantoin metabolites acting as heptanes and resulting a hypersensitivity react...

Fatal nitrofurantoin lung.

Nitrofurantoin is a drug commonly used for urinary tract infections. It acts by damaging bacterial DNA. It is given in dose of 50-100 mg orally and is generally considered a safe drug but has occasionally been known to cause pulmonary toxicity which is usually reversible and only rarely fatal. We present a case of an elderly lady receiving nitrofurantoin for her urinary tract infection who deve...

Fatal haemorrhage from mycotic aneurysms of the pulmonary artery.